A lot of electronic hobby types use
Eagle.
The big drawback with it an most electronics cad programs is finding the parts you want to use in their libraries. The other is that the free version of Eagle limits the board size and can not be used commercially.
With eagle you first layout the schematic then the PCB layout program uses the schematic to prevent you from making mistakes. It does not create the board automatically from the schematic. Just forget about doing that. It takes a person on a very expensive program to do good automated layout.
Spice is a circuit simulator. The latest version of eagle have a tie in to spice. You have to use new, special, libraries that have both spice and eagle information for the parts.
A good place to find help is the
ElectroTechOnline forum.